Disease: Tubulointerstitial fibrosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VPS51 Q9UID3 VPS51 subunit of GARP complex 1.1E-08 0.452 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
TGFBI Q15582 transforming growth factor beta induced Signaling 6.0E-08 0.484 0.769
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
SLC33A1 O00400 solute carrier family 33 member 1 Transporter 9.9E-05 0.529 0.769
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
PGR-AS1 PGR antisense RNA 1 0.514 0.808
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
MMRN1 Q13201 multimerin 1 2.1E-25 0.465 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923